Cha Jeong Woo (Lee Min Ki) is one of the best plastic surgeons in the country, possessing great anatomical knowledge and surgical skill. However, his bedside manner is sorely lacking, and he's known for his poor communication towards patients. His reputation comes crashing down when a suicide case was linked to his refusal of a patient's surgery. To rehabilitate his image, Jeong Woo starts working on a new group of patients – victims of violent crimes who need reconstructive surgery. In the process, Jeong Woo crosses paths with homicide detective Lee Min Hyeong (Han Ji Hyeon), and while they initially butt heads, they begin to respect each other as Jeong Woo helps Min Hyeong solve crimes. However, during their investigations, an old mystery resurfaces: is there something more behind the incident that cost Jeong Woo's past lover her life?

Hae Yi is a freshman at Yonhee University in the year 2019. As she comes from a poor family, she focuses mainly on earning money. She joins the Theia Cheerleading Squad just for the purpose of making money, but happens to learn true love there. Jung Woo is a senior student at Yonhee University and is also the leader of Theia. Being a principled student with a warm heart, he leads the squad in need despite his exam studies. Sun Ho is a Medical School freshman who has always been an elite student. However, he feels something that he never felt before when meeting Hae Yi at the cheerleading squad. The future of Theia and the relationships of these young students will unravel soon.

Su Ryeon finally takes revenge on the residents of Hera Palace. They lost all of their money by investing in Cheonsoo District, and even worse, they stand before the court for covering up Seol A's death. Those greedy residents of Hera Palace who caught themselves in their own traps end up losing their fortunes, reputations, and everything they had, and Su Ryeon succeeds in getting her revenge on Dan Tae who tried to kill her. When Su Ryeon thought the nightmare is finally over, she witnesses Logan's death right before her eyes. Who could have planned to murder Logan, and what will happen to the residents of Hera Palace next? Their desire for revenge is not over yet.

Seo Jin and Dan Tae eventually get rid of everyone who was in their way. They shamelessly frame Yoon Hee for the murder of Su Ryeon and even cover up the death of Seol A. The residents of Hera Palace believe everything will return to how it used to be. However, the tides change when Yoon Hee escapes prison and Eun Byeol discovers the truth. Their mysterious fates are still yet to be seen. Will they manage to protect their precious palace until the very end?